Attention Deficit Hyperactivity Disorder or ADHD	A common developmental and behavioural disorder. It is characterised by poor concentration, distractibility, hyperactivity and impulsiveness that are inappropriate
Bipolar Disorder or Bipolar Affective Disorder or manic depression	A disorder in which a person can experience recurrent attacks of depression and mania or hypomania
Clinical	The phase of pharmaceutical R&D in which drug candidates are tested on humans under the control of clinicians
CNS	The human central nervous system
Compliance rates	The proportion of patients demonstrating compliance to a treatment regime. Compliance may be expressed as the proportion of days when the prescribed number of drug doses were taken
Disease mechanism	A biological mechanism underlying a human disease
Drug therapy	The treatment of disease by the administration of drugs, chemicals or antibiotics
Efficacy	The capacity of a drug or drug candidate to produce a desired effect; drug effectiveness
Genomics	The study of genes and their role in an organism's structure, growth, health and disease
Homomatrix®	Curidium's proprietary research technology, designed to identify underlying disease mechanisms as well as novel drug treatments and diagnostic tests for appropriate patient sub-groups
Novel applications	New use or therapeutic appliance of a drug or drug candidate
Novel diagnostic tests	A newly developed assay to be conducted for diagnostic purposes; a novel quantitative or qualitative test used to diagnose, analyse or identify a specific disease or condition
Novel indications	Newly identified therapeutic use of a drug or drug candidate in a particular disease or condition
Personalized medicine	The ability to offer the appropriate treatment to the right person
Pharmacogenomics	Branch of pharmaceutics which deals with the influence of genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with a drug's efficacy or toxicity
Preclinical	The phase of pharmaceutical R&D where laboratory studies are designed to test the mechanisms, safety, and efficacy of a drug candidate prior to its applications to humans
Proteomics	Proteomics is the study of protein properties on a large scale to develop a more comprehensive understanding of cellular processes, disease and networks
PsychINDx™	Curidium’s proprietary blood diagnostic test that enables the classification of a schizophrenia or bipolar disorder patient into of four different subgroups
Regulatory	The marketing approval and registration process for new products by the Food and Drug Administration (US), the European Agency for the Evaluation of Medicinal Products or a similar organisation
Schizophrenia	A mental disorder characterised by loss of contact with reality (psychosis), hallucinations (usually, hearing voices), delusions (false beliefs), abnormal thinking, flattened affect (restricted range of emotions), diminished motivation and disturbed work and social functioning
Strategic Research Alliance	A collaborative research partnership with a pharmaceutical or biotechnology company
Targeted medicine	Prevention and earlier detection of disease and the tailoring of treatments to patients based on genetic factors and understanding the molecular basis of disease. Encompasses new diagnostic tests to help physicians predict, characterise, monitor, and select therapies. This new paradigm is sometimes referred to as personalised medicine